Skip to content
Warehouse Shutdown Notice: Orders placed between Boxing Day and 2 Jan will ship after we resume operations. Thanks for your patience.

PPE Removal Guide | Ensuring Safety First

19 Dec 2025 0 comments

Understanding PPE and the Significance of Proper Removal Order

Personal protective equipment (PPE) encompasses essential items like respirators, gloves, gowns, and eye/face protection, serving as critical barriers to hazards, safeguarding skin, mouth, nose, or eyes. OSHA mandates risk assessment for employers, necessitating suitable controls, including PPE deployment when required according to its PPE regulation 29 CFR 1910.132.

NIOSH offers a robust framework for evaluating and certifying various safety devices, particularly respirators, via its NPPTL program. These resources empower buyers with evidence-informed choices (CDC/NIOSH NPPTL). Proper PPE selection and fitting are vital for ensuring safety across numerous industries such as healthcare, construction, manufacturing, laboratories, utilities, and public services.

When using PPE, contaminants can gather on exterior surfaces. Handling these before cleansing hands may transport pathogens to mucous membranes or untainted attire. Following an accurate PPE removal order mitigates self-contamination by prioritizing the removal of the most contaminated items first, incorporating hand hygiene within the process. The CDC’s thoughtful doffing sequence is grounded in years of infection prevention research and practical application, setting a dependable foundation for policies, training, and inspections (CDC HAI PPE sequence PDF).

Final PPE items to remove are respirators or masks, as dictated by CDC, ensuring the removal occurs outside patient or care zones. Before handling straps, perform hand hygiene and avoid touching the front, following up with another hand cleanse (CDC HAI PPE sequence PDF). Eye protection comes off before masks or respirators, while gloves and gowns are removed earlier. Organizations conducting aerosol-generating activities must align with respiratory safety regulations for fit testing, seal checks, and doffing procedures under OSHA 29 CFR 1910.134.

Documented PPE strategies should outline product specifications, sizing, donning and doffing protocols, hand hygiene timing, discard procedures, and oversight requirements. Visual instruction aids, routine practice exercises, and competency evaluations bolster adherence. Utilizing standardized displays or job aids from CDC and NIOSH elevates consistent training, purchasing choices, and quality compliance among staff (CDC/NIOSH NPPTL; CDC HAI PPE sequence PDF). Such measures render PPE removal sequences predictable, traceable, and manageable under challenging conditions.

Step-by-Step Guide to Safe PPE Removal

In environments where the risk of contamination is high, such as healthcare settings, proper removal of Personal Protective Equipment (PPE) is crucial to minimize exposure and prevent the spread of infectious agents. Adhering to the Centers for Disease Control and Prevention (CDC) guidelines provides a structured and effective process for removing PPE safely. This ensures reduced risk of self-contamination during high-exposure tasks.

Preparation Stage

Establish a designated area for doffing at the room's threshold to maintain workflow efficiency and safety. A CDC visual aid should be posted nearby, serving as a quick reference for the proper sequence of removing protective gear. Ideally, a trained observer can assist in this process. Disinfect all visibly soiled contact points prior to starting the doffing process. Preemptive steps including placement of waste bins with accessible lids, performance of hand hygiene, and inspection of all PPE for integrity issues are necessary. Brief the team on the sequence to ensure cohesive execution.

CDC-aligned PPE Removal Sequence

The following steps, reflective of CDC guidelines, are tailored for routine healthcare use. Always prioritize facility-specific protocols alongside these suggestions:

  1. Glove Removal: Remove the outer hand protection carefully, avoiding skin contact.
  2. Gown Removal: Unfasten waist ties smoothly, avoiding snags. Gently release neck fastenings. Roll the gown inside-out, ensuring a tight roll, and discard into a designated waste bin.
  3. Hand Hygiene: Thoroughly clean your hands with an alcohol-based rub.
  4. Exit the Care Area: Completely vacate the immediate room.
  5. Face Shield or Goggles: Lift the face shield using the strap only; do not touch the front. If goggles are reusable, clean them per facility policy before storage.
  6. Hand Hygiene Repeated: Again, perform hand sanitization until dry.
  7. Respirator or Mask Removal: Detach respirator or mask as the final step.
  8. Final Hand Hygiene: Complete hand hygiene one last time at the designated station.

This procedure reduces contamination by addressing PPE in order of most to least contaminated items. Reference: CDC Guidelines.

Technique Aids and Controls

Ensure movements during doffing are slow and deliberate to minimize the risk of aerosol and droplet spray. Maintain strict hand-off-face discipline. In the case of torn gloves, replace immediately, followed by hand re-cleaning. A mirror can aid in self-monitoring during removal. Consult an observer if uncertain. Reusable respirators should be bagged and labeled to prevent misuse. Spills? Clean floors promptly to prevent cross-contamination. Routine audits can spot practice gaps, while frequent drills reinforce the removal sequence. Follow facility SOPs based on current CDC and OSHA guidelines.

Handling of Waste and Post-Doffing Hygiene

Safely discard waste in accordance with OSHA's Bloodborne Pathogens Standard. Move reusable items promptly to the decontamination area. Exposure incidents need documentation for review and prevention strategy improvement. PPE should be restocked immediately following exit to ensure readiness for subsequent use. Hands must air-dry completely before another glove pair is donned. Ensure the workstation is prepared for the next individual.

To maintain robust safety standards, training refreshers should be conducted quarterly, observers validated annually, and SOPs updated following any significant protocol changes from CDC or OSHA.

---

Importance of Removing Respiratory PPE Last

Understanding the order of removing personal protective equipment (PPE) is essential for minimizing exposure risks, particularly in settings where airborne contaminants pose significant threats. Respiratory protection must be the last piece removed to ensure that airway protection remains intact during the handling of other protective layers such as gloves and gowns. This strategy is vital as removing outer layers often results in particles becoming airborne, potentially lingering close to the face if respiratory protection is not prioritized.

The Centers for Disease Control and Prevention (CDC) emphasizes this sequence in its PPE removal guidelines to protect workers effectively. Their logic rests on minimizing inhalable risks and avoiding face-to-hand contamination that can occur if hands are not cleaned thoroughly after other PPE is taken off. A visual sequence from the CDC can be found here.

When gloves or gowns are removed, aerosol contaminants are easily re-suspended in the air. By keeping masks or respirators on until exiting areas where contamination might persist, exposure risk decreases significantly. This practice helps fend off residual contact to mucous membranes, eyes, or other sensitive areas of the face.

The Occupational Safety and Health Administration (OSHA) mandates the adoption of comprehensive PPE programs. These include training on proper doffing techniques to lessen the likelihood of exposure during handling. Information on these requirements can be accessed here.

Facilities are guided by CDC and National Institute for Occupational Safety and Health (NIOSH) research, which indicates that improper doffing can often lead to self-contamination. An article on these findings can be reviewed here.

Why the Final Removal of Respiratory Masks and Respirators is Essential:

  • Controls the re-suspension of aerosols when gowns are taken off.
  • Protects against transfer to mucosa when hands may still carry contaminants from other PPE.
  • Maintains filtration active until fully departing patient zones or decontamination points.
  • Lowers risk from accidental splashes, movements from coworkers, or procedural errors.
  • Ensures hands are sanitized before touching straps; lean forward slightly to avoid front contact.
  • Limits exposure while removing goggles or face protection, preparing for disposal, or storage.

Recommended PPE Removal Sequence:

  1. Gloves
  2. Gown or apron
  3. Perform hand hygiene
  4. Eye/face protection (e.g., goggles or face shield)
  5. Mask or respirator
  6. Perform hand hygiene again

Good practice includes leaning forward, handling straps only, and avoiding touching the front before discarding or storing the mask according to facility SOPs. Further guidance is available in the CDC’s poster here. Adhering to OSHA standards ensures comprehensive training and implementation of proper PPE removal steps, detailed here.

Ultimately, residual contaminants can remain until hygiene measures are completed, making the retention of respiratory protection until all other PPE is removed a necessary protocol for health and safety.

---

Frequently Asked PPE Removal Questions

Clear, evidence-led protocols on removing personal protective equipment (PPE) can significantly reduce exposure risks during the doffing process. This guidance draws on expert resources from the CDC, OSHA, WHO, and the APIC.

What is the correct sequence for removing PPE according to CDC?

The CDC provides a specific sequence: first, remove gloves; next, take off the gown; exit the patient room or care area if needed; perform hand hygiene; remove face shield or goggles; remove mask or respirator; and perform hand hygiene again. Visual aids and additional notes on the proper sequence and room exit or respirator timing are available in the CDC’s "Sequence for Removing Personal Protective Equipment" poster: CDC PPE Sequence. Broader PPE use details can be found here.

How can self-contamination be avoided during doffing?

Create a designated doffing zone with a waste bin accessible. Move deliberately and avoid contact with the front of gowns, masks, face shields, or goggles. Employ glove-in-glove and gown-peel techniques while handling straps or ear loops only. Perform hand cleaning after each step and upon exit. WHO’s job aid offers additional reinforcement for safe practices: WHO PPE Guide).

Where should respirators be removed?

For airborne precautions, respirators should be removed after exiting the patient room. Avoid contact with the filter surface, handling only the respiratory headbands. Clean hands both before and after removal. CDC infection control notes expand on these precautions: CDC Precautions.

How should used items be discarded?

Promptly place disposable PPE into the appropriate waste stream, ensuring contents remain uncompressed. Containers should be securely closed before transport, with immediate hand cleaning afterward. OSHA guidelines on bloodborne pathogens detail regulated waste, appropriate containers, and labeling: OSHA PPE Guidelines.

What training encourages safer PPE performance?

Competency-based drills with trained observers, checklists posted at doffing points, and regular refresher sessions underpin effective practices. APIC offers a hub of PPE resources including step-by-step job aids and policy templates: APIC PPE Resources. CDC’s Project Firstline features modules on doffing risks for frontline workers: CDC Project Firstline.

Any quick PPE removal FAQs for non-clinical worksites?

Install mirrors in doffing areas, ensure clean hand rub is staged, keep waste bins nearby, and assign a spotter during high-risk activities. OSHA’s PPE portal provides specific guidelines for various industries: OSHA PPE Portal.

For further guidance on PPE removal, bookmarking APIC’s tools along with CDC's visuals can help standardize doffing practices across different work shifts.

Prev post
Next post

Leave a comment

Please note, comments need to be approved before they are published.

Thanks for subscribing!

This email has been registered!

Shop the look

Choose options

Edit option
Have Questions?
is added to your shopping cart.

Choose options

this is just a warning
Login